Endocrine Abstracts

Background: The aim of this study was to explore if evaluation of lipid risk factors like Lipoprotein(a) (Lp(a)) and conventional lipid profile parameters can be a efficient predictor of the cardiovascular risk in the patients of Diabetes.Methods: Sixty individuals with angiographically proven premature CAD and 30 healthy individuals matched for age and sex were studied a tertiary health care centre, New Delhi, India, over a period of 18 months. CAD pati...

Background: The aim of this study was to explore if evaluation of lipid risk factors like Lipoprotein(a) (Lp(a)) and conventional lipid profile parameters can be a efficient predictor of the cardiovascular risk in the patients of Diabetes.Methods: Sixty individuals with angiographically proven premature CAD and 30 healthy individuals matched for age and sex were studied a tertiary health care centre, New Delhi, India, over a period of 18 months. CAD pati...

Issues: This is non-interventional, Demographic, observational study in asian population. Osteoporosis common in Developing-nations. Not-a-single Center exist designated for diagnosis/treatment. No proper epidemiological, mortality/morbidity data available. In asian population Osteoporosis is diagnosed at advanced stage hence poor-prognosis. Worsened by High incidence of malnourished. Increased awareness/improved diagnosis needed to identify cases.Aim: T...

Issues: No specific centre in asia for Osteoporosis patients treatment/rehabilitation. We used locally available Complementary Indian Medicines [CAM] for providing home based care in rural/tribal areas.Aims: To provide CAM to poor patients in collaboration with Traditional-faith-hearers. Evaluated cost-efficacy of CAM & response of pain of fractures to CAM alongside analgesics.Methods: This was a cross sectional, observational ...

GH therapy has been reported to increase insulin resistance, but overt diabetes is rare. We present a young girl who developed symptoms of diabetes whilst on GH therapy with resolution of symptoms and normalisation of blood glucose profile on reducing the dose of GH.Case report: A 14-year-old girl with background of prematurity, learning difficulty, cerebral palsy, scoliosis, and pan hypopituitarism presented with chest infection, high blood glucose leve...

Studies show conflicting results regarding possible excess risk of atypical fractures associated with bisphosphonate (BSP) use. Since BSP reduces bone remodeling, they freeze the skeleton allowing accumulation of microcracks over time leading to atypical fractures. We present two cases of atypical fracture and discuss on monitoring therapy and drug holiday in chronic BSP users.Methods: Over the period of last 8 months we diagnosed two cases of alendronat...

Introduction: Primary Hypoparathyroidism presents most commonly in childhood to early adolescence. Disease may be familial or sporadic.Most commonly hypoparathyroidism is secondary to neck operations especially Thyroid surgeries. Primary can be congenital eg- Digeorge syndrome or inherited by AD, AR or X linked mediated.We report 2 cases of late onset seizure due to Digeorge syndrome and Autosomal Dominant Hypoparathyroidism in a elderly lady.Case Report...

Introduction: The Nephrogenic syndrome of inappropriate antidiuresis (NSIAD) is an X-linked condition characterised by reduced renal water clearance and hyponatraemia resulting from gain of function mutations in the type 2 Vasopressin (AVP) receptor (AVPR2). Female carriers were thought not to express a phenotype. We describe a kindred with NSIAD, highlighting molecular and physiological characteristics that extend understanding of this condition and of AVP production.<p c...

Increased hypothalamic-pituitary-adrenal (HPA) activity in the fetus is a consistent event across different animal species, including the human. Fetal HPA activation contributes both to maturation of organ systems required for extra-uterine life and provides the trigger for the birth process. Precocious activation of the fetal HPA axis, for example in response to an adverse intrauterine environment or periconceptual undernutrition may result in increased incidence of preterm b...